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What is Amiodarone?
Amiodarone is a medication used to treat a fast or irregular heartbeat.
How do I take the medicine?
You should always take your Amiodarone as directed by the label on the box. It is common to start with a higher dose for the first one to two weeks to help the medicine work effectively.
The typical starting dose is one 200mg tablet three times a day for one week, followed by one 200mg tablet twice a day for one week, and then reducing to one 200mg tablet daily. You should aim to take the tablets at the same time each day with a glass of water.
What if I forget to take a tablet?
If you forget to take a tablet, take one as soon as you remember on the same day. However, if it is nearly time for your next dose, skip the missed one and take your next tablet as usual. Do not take a double dose to make up for a missed one.
What are the side-effects of Amiodarone?
Amiodarone is a very effective medicine, but like all medications, it can have side effects.
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Skin: Amiodarone can make your skin more sensitive to the sun while you are taking it and for a few weeks after stopping. You should avoid direct sunlight and sunbeds. Protect your skin by using a total sunblock, wearing a sun hat, and keeping your arms and legs covered. The medication can also cause a greyish/blue tinge to the skin, which should resolve after you stop taking it.
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Thyroid: Amiodarone can affect your thyroid, making it overactive or underactive. If you experience extreme tiredness or restlessness, it is important to see your doctor. Your doctor will monitor your thyroid function with a blood test before you start treatment and every six months thereafter.
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Liver: Although very rare, Amiodarone can cause liver problems. Your doctor will check your liver function with a blood test before you start and every six months during treatment. Contact your doctor if you experience any signs of liver problems, such as yellowing of the skin or mucous membranes, itchy skin, nausea, or vomiting.
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Lungs: Lung problems are a very rare side effect. Please see your GP immediately if you become short of breath or develop a persistent cough. A chest X-ray is often done before starting treatment, and pulmonary function tests may be arranged if your doctor thinks they are necessary.
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Eyes: Small, harmless deposits can form in the cornea of the eye, which usually disappear when you stop the medication. These do not affect daytime vision but may cause you to be dazzled by bright lights at night. Some people notice a bluish halo around their vision, which is not harmful. However, if you experience any impairment in your vision, you must see your doctor immediately. It is important to attend a yearly eye test while taking Amiodarone.
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Other Side Effects: Other rare side effects include a metallic taste in the mouth, pins and needles, and sleep disorders.
Interactions and Monitoring
Many medicines can interfere with how Amiodarone works. Always inform your doctor and pharmacist if you start or stop any other medicines. You should also avoid grapefruit juice while taking Amiodarone, as it can increase the amount of the medication in your body.
Your GP will monitor your treatment every six months with blood tests to check your liver and thyroid function.
Further Information
How should I store my medicine?
Store your tablets in a cool, dry place, out of the sight and reach of children.
How long should I continue to take the tablets?
Continue taking the tablets for as long as your doctor prescribes them. Ensure your medication is reviewed regularly by your doctor and that you attend your six-monthly blood tests.
Where do I get more tablets?
You can get more tablets from your GP. Make sure to get a new supply before you run out.
What if I have more questions?
If you need more advice or information, please ask your doctor or pharmacist. You can also call the Medicines Information Helpline, Monday to Friday from 2-4 pm, on 01302 553201.
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